David Craig, a biotechnology founder and longtime industry operator, has released 'The New Rules of Biotech: A Founder's Guide to Building Great Companies' in hardcover ($29.99) and as an audiobook on Google Play. These additions join the previously available paperback ($21.99) and Kindle ($11.99) editions on Amazon, offering founders, investors, board members, and operators multiple formats to access the material.
The book addresses a fundamental shift in the biotech industry: the playbook from 2021 no longer applies. Capital is more expensive, the FDA bar has moved, and the Inflation Reduction Act has altered the economics of drug development before approval. Investors now prioritize capital efficiency and a clear path to value over ambitious slide decks. 'The New Rules of Biotech' serves as an operating manual for building companies under these conditions.
Drawing from his experience founding and running a preclinical biotech, Craig outlines practical strategies for modern company building. Topics include choosing between a platform and an asset, selecting an affordable modality, raising a seed round based on milestones rather than hope, and using non-dilutive capital strategically. The book guides readers through IND-enabling work, CMC, clinical decisions, term sheets, boards, business development, acquisitions, and IPOs, without sentimentality.
Written for founders, institutional investors, board members, and operators, the book pairs an analytical voice with actionable specifics. Each chapter closes with takeaways for operators and a separate section for investors and advisors, making it useful for both sides of the table. The new audiobook format allows listeners to absorb the content on the go.
The book's origin is personal: Craig founded his company partly due to a family connection to RYR-1 related congenital muscular dystrophy, a rare genetic muscle disease. This connection underscores his argument that biotech company building carries responsibilities beyond financial returns.
'Founders and operators take in ideas in different ways,' said David Craig. 'The hardcover is there for the people who want a durable copy on the desk, the paperback and Kindle for everyone else, and the audiobook on Google Play for those who prefer to listen on the move. The message is the same across all of them: build for the market that exists now, not the one that existed in 2021.'
'The New Rules of Biotech: A Founder's Guide to Building Great Companies' is published by D. Craig Consulting LLC and is available at Amazon in hardcover, paperback, Kindle, and audiobook on Google Play.
